DSPE-PEG-NHS，DSPE-PEG-SS

商品型号：YZY2-HDE-1K,2K,3K,5K,10K

英文简称：1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[Succinimidyl Succinate ester(polyethylene glycol)]

分子量：1K,2K,3K,5K,10K

规格：500mg,1g

DSPE-PEG-NHS，DSPE-PEG-SS

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[SuccinimidylSuccinate ester(polyethylene glycol)]

Synonym: 1,2-Distearoyl-sn-Glycero-3-PhosphoethanolaminePEG NHS, NHS PEG DSPE, DSPE PEG Succinimidyl Succinate ester, DSPE Polyethyleneglycol NHS.

ProductStructure:

ProductSpecifications:

CatalogNumbers:PS2-HDE-1K,2K,3K,5K,10K.

Appearance: Whiteto off-white solid.

Solubility: 10mg/mL in hot water, chloroform, DCM, DMSO.

Stability: 1 Years at-20°C, Desiccate.

CASNumber: -

MolecularWeight（PEG）:1K,2K,3.4K,5K,10K.

Reactivegroup: NHS.

Reactiveto: Primary amine (-NH2).

Purity: 95%.

Description:

DSPE-PEG-NHS is one of reactive phospholipid PEG conjugates that can react with primary amine groups.DSPE(1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbonphospholipid that is highly hydrophobic. PEG backbone, on the other hand,offers good hydrophilicity and water solubility. Succinimidyl ester (NHS) onthe PEG terminal reacts with primary amine groups efficiently at pH 8~10. DSPE-PEG-NHS can be easily incorporatedinto liposome and other nanoparticles. DSPE-PEG-NHS is one of most commonly used reactive phospholipids to conjugate antibodies,peptides or other ligands to the surface of liposome and other lipid PEGnanoparticles. Pegylated phospholipids have longer blood circulation time andhigher stability for encapsulated molecules.

Handlingand Use:

DSPEPEG NHS should always be kept in low temperature in dry condition. Prepare freshsolution right before use.Avoid frequent thaw and freezing. For moreinformation about using this product,

RelatedProducts:

DSPE-PEG-NH2,DSPE-PEG-COOH

DSPE-PEG-N3,DSPE-PEG-FA

DSPE-PEG-SH,DSPE-PEG-MAL

References：

Biomimeticvirus-like and charge reversible nanoparticles to sequentially overcome mucusand epithelial barriers for oral insulin delivery------ Acsapplied materials&interfaces（IF=8.097）

Thecombination of endolysosomal escape and basolateral stimulation to overcome thedifficulties of “easy uptake hard transcytosis” of ligand-modifiednanoparticles in oral drug delivery------ Nanoscale（IF=7.233）

Colorimetricin situ assay of membrane-bound enzyme based on lipid bilayer inhibition of iontransport------ Theranostics（IF=8.537）

Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.