Methoxy-PEG-acid，MPEG-COOH

商品型号：YZY1-CM-350,550,750,1k,2k,5k,10k,20k,30k

英文简称：Methoxy (polyethylene glycol) Carboxylic acid

分子量：350,550,750,1k,2k,5k,10k,20k,30k

规格：1g,5g

Methoxy-PEG-acid，MPEG-COOH

Methoxy (polyethylene glycol) Carboxylicacid

Synonym: mPEG-COOH,mPEG acid, Methoxypolyethylene glycol acid, PEG acid

ProductStructure:

ProductSpecifications:

CatalogNumbers:PS1-CM-350,550,750,1k,2k,5k,10k,20k,30k.

Appearance: White/off-whitesolid, semi-solid or liquid depends on molecular weight.

Solubility: 10mg/mL in water,chloroform, DMSO.

Stability: 1 Years at -20°C, Desiccate.

LinearFormula：CH3O(CH2CH2O)nCH2COOH.

MolecularWeight（PEG）: 350,550,750,1k,2k,5k,10k,20k,30k.

Reactivegroup: COOH

Reactiveto: NH2

Purity:> 95%.

Description:

MPEG-COOH is one of carboxylic acid (-COOH) functionalized polyethyleneglycol derivatives that can be used to modify proteins, peptides, particles andother materials with their free acid group. Carboxylic acid groups react readilywith amine groups to form stable amide bond. They can also react with hydroxylgroups to form labile ester bond which can be cleaved under acidic or basic conditions.PEGylation can increase solubility and stability and reduce immunogenicity ofpeptides and proteins. It can also suppress the non-specific binding of chargedmolecules to the modified surfaces. Acid functionalized PEG has broadapplications in the field of medical device modification, biomoleculepegylation and particle surface functionalization.

Handlingand Use:

MPEG-COOH is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.

Avoid frequent thaw and freezing. For moreinformation about using this product,

StorageConditions：

MPEG-COOH should bestored at -20℃.Desiccate. Materials may be handledunder inert gas for best stability. Re-testmaterial after 12 months.

References：

SizeChangeable Nanosystems for Precise Drug Controlled Release and EfficientOvercoming of Cancer Multidrug Resistance------Journalof Materials Chemistry B (IF=4.776)

Angiopep-2modified PEGylated 2-methoxyestradiol micelles to treat the PC12 cells withoxygen-glucose deprivation/reoxygenation------Colloidsand Surfaces B: Biointerfaces (IF=3.997)

PEGylateddoxorubicin cloaked nano-graphene oxide for dual-responsive photochemicaltherapy ------ International Journalof Pharmaceutics (IF=3.862)

RelatedProducts:

BIOTIN-PEG-NH2, DSPE-PEG-NH2

NH2-PEG-SH ,FA-PEG-NH2

FITC-PEG-NH2,LA-PEG-NH2

Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.