Silane-PEG-acid，Silane-PEG-COOH

商品型号：YZY2-CML-1K,2K,3.4K,5K,10K

英文简称：Silane (polyethylene glycol) Carboxylic acid

分子量：1K,2K,3.4K,5K,10K

规格：1g,5g

Silane-PEG-acid，Silane-PEG-COOH

Silane (polyethylene glycol) Carboxylicacid

Synonym: Silane PEGacid, Carboxylic PEG Silane, Triethoxysilane PEG acid, Trimethoxysilane PEGacid

ProductStructure:

ProductSpecifications:

CatalogNumbers:PS2-CML-1K,2K,3.4K,5K,10K.

Appearance: White/off-whitepale-yellow solid.

Solubility: 10mg/mL in water,chloroform, DMSO.

Stability: 6months at -20°C, Desiccate.

MolecularWeight（PEG）: 1K,2K,3.4K,5K, 10K.

Reactivegroup: COOH

Reactiveto: NH2

Description:

Silane-PEG-COOH is one of surface reactive polyethyleneglycol silanization and pegylation reagents that contain a terminaltriethoxysilane and a carboxylic group. Silane PEG COOH can be used to modifyglass, silica and other surfaces via the reaction between hydroxyl group and alkoxylsilane groups. Triethoxyl or trimethoxyl silane reacts with OH groups easilywith catalytic amount of water. Meanwhile, carboxylic group can be activated toreact with amine or hydroxy groups. PEG linker between alkoxysilane andmaleimide group offers better water solubility, less steric hindrance andenhanced reactivity. Compared to other organic silanes, Nanocs’ silane PEGs aresoluble in aqueous solution, all silanization reactions can be performed inaqueous solution without adding any organic solvents. Alkoxyl groups hydrolyzereadily in aqueous solution and reaction can be completed at room temperaturein 30~60 min.

Handlingand Use:

Silane-PEG-COOH is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.

Avoid frequent thaw and freezing. For more informationabout using this product,

StorageConditions：

Silane-PEG-COOH should bestored at -20℃.Desiccate. Materials may be handledunder inert gas for best stability. Re-testmaterial after 6 months.

References：

FunctionalizedHolmium-Doped Hollow Silica Nanospheres for Combined Sonodynamic andHypoxia-Activated Therapy------Advanced functionalmaterials (IF=13.325)

Identifyingmacrophage enrichment in atherosclerotic plaques by targeting dual-modal USimaging/MRI based on biodegradable Fe-doped hollow silica nanospheresconjugated with anti-CD68 antibody------Nanoscale (IF=7.233)

RelatedProducts:

BIOTIN-PEG-COOH, DSPE-PEG-COOH

NH2-PEG-COOH ,FA-PEG-COOH

FITC-PEG-COOH,HS-PEG-COOH

Thisproduct is for research use only and is not intended for use in humans or for diagnosticuse.