Thiol-PEG-acid，HS-PEG-COOH

商品型号：YZY2-SCM-400,600, 1K,2K,3.4K, 5K, 10K

英文简称：Thiol (polyethylene glycol) Carboxylic acid

分子量：400,600, 1K,2K,3.4K, 5K, 10K

规格：1g,5g

Thiol-PEG-acid，HS-PEG-COOH

Thiol (polyethylene glycol) Carboxylicacid

Synonym: Thiol PEGacid, Carboxylic acid PEG Thiol, HOOC-PEG-SH

ProductStructure:

ProductSpecifications:

CatalogNumbers:PS2-SCM-400,600, 1K,2K,3.4K, 5K, 10K.

Appearance: White/off-whiteor pale-yellow solid, semi-solid or liquid depends on molecular weight.

Solubility: 10mg/mL in water,chloroform, DMSO.

Stability: 1 Years at -20°C, Desiccate.

LinearFormula：HSCH2CH2(CH2CH2O)nCH2COOH.

MolecularWeight（PEG）: 400,600,1K,2K,3.4K, 5K, 10K.

Reactivegroup: SH.COOH

Reactiveto: MAL,NH2

Purity:> 95%.

Description:

HS-PEG-COOH is one of reactive thiol PEG derivatives that have a terminal carboxylic group.Carboxylic groups can react with amine or hydroxyl groups to form a stableamide bond or a labile ester bond. Reactions of carboxylic group allow theconversion of amine or hydroxyl groups to free thiols with a linear PEG linker.Resulted thiol groups can be used to modify gold nanoparticle surface or participatein other pegylation reactions. PEG linker between thiol and carboxylic groupoffers good water solubility, flexible linker distance and higher stability.

Handlingand Use:

HS-PEG-COOH is sensitive to light and temperature. Forbest use, material should always be kept in low temperature in dry condition.

Avoid frequent thaw and freezing. For moreinformation about using this product,

StorageConditions：

HS-PEG-COOH should bestored at -20℃.Desiccate. Materials may be handledunder inert gas for best stability. Re-testmaterial after 12 months.

References：

ALight-Triggered Mesenchymal Stem Cell Delivery System for Photoacoustic Imagingand Chemo-Photothermal Therapy of Triple Negative Breast Cancer------ Advanced science (IF=12.441)

Apara-Aminothiophenol Radical Reaction-Functionalized Gold Nanoprobe forOne-to-All Detection of Five Reactive Oxygen Species in Vivo------Analytical Chemistry (IF=6.042)

Colorimetricand visual determination of acrylamide via------Microchim Acta (IF=5.705)

A noveldisulfide bond-mediated cleavable RGD-modified PAMAM nanocomplex containingnuclear localization signal HMGB1 for enhancing gene transfection efficiency------ InternationalJournal of Nanomedicine (IF=4.37)

RelatedProducts:

BIOTIN-PEG-SH, DSPE-PEG-SH

NH2-PEG-SH ,FA-PEG-SH

HS-PEG-NHS,N3-PEG-SH

Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.