DSPE-PEG-COOH，DSPE-PEG-Acid

商品型号：YZY2-CMDE-1K,2K,3K,5K,10K

英文简称：1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethylene glycol)]

分子量：1K,2K,3K,5K,10K

规格：500mg,1g

DSPE-PEG-COOH，DSPE-PEG-Acid

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carboxy(polyethyleneglycol)]

Synonym: DSPEPEG acid, Carboxylic PEG DSPE

ProductStructure:

ProductSpecifications:

CatalogNumbers:PS2-CMDE-1K,2K,3K,5K,10K.

Appearance: Whiteto off-white solid.

Solubility: >10mg/mL in hot water, chloroform, DCM.

Stability: 1 Years at-20°C, Desiccate.

CASNumber: 1403744-37-5

MolecularWeight（PEG）:1K,2K,3.4K,5K,10K

Reactivegroup: Carboxylic acid (-COOH).

Reactiveto: Primary amine group (-NH2)

Purity: 95%.

Description:

DSPEand acid is one of reactive phospholipid PEG derivatives. DSPE(1,2-distearoyl-sn-glycero-3-phosphoethanolamine) is an 18 carbon phospholipidthat is highly hydrophobic. PEG backbone, on the other hand, offers goodhydrophilicity and water solubility. Carboxylic functionalized DSPE PEG hasexcellent reactivity towards amine or hydryoxyl groups. Carboxylic PEG DSPE isone of most commonly used reactive phospholipids to conjugate antibodies,peptidesor other ligands to the surface of liposome and other lipid nanoparticles.Pegylation of phospholipids significantly increases the blood circulation timeand stability for encapsulated drugs. has developed a comprehensive collectionof reactive phospholipid PEG products that have high purity, various molecularweights and excellent chemical reactivity. These lipid PEG conjugatesdemonstrate excellent amphilphilic properties and offer superior advantages forsmall and large molecule labeling, formulation and delivery.

Handlingand Use:

DSPE PEG acid shouldalways be kept in low temperature in dry condition. Prepare fresh solutionright before use.Avoid frequent thaw and freezing. For more information aboutusing this product,

RelatedProducts:

DSPE-PEG-NH2,DSPE-PEG-OPSS

DSPE-PEG-NHS,DSPE-PEG-FA

DSPE-PEG-SH,DSPE-PEG-MAL

References：

Transportmechanisms of butyrate modified nanoparticles: insight into “easy entry, hardtranscytosis” of active targeting system in oral administration------Molecularpharmaceutics(IF=4.556)

Enhancedcellular uptake of near-infrared triggered targeted nanoparticles by cellpenetrating peptide TAT for combined chemo/photothermal/photodynamic therapy------ MaterialsScience and Engineering C(IF=5.08)

Bioinspiredbutyrate-functionalized nanovehicles for targeted oral delivery ofbiomacromolecular drugs------ Journal of ControlledRelease（IF=7.877）

NIRstimulus-responsive core–shell type nanoparticles based on photothermalconversion for enhanced antitumor efficacy through chemo-photothermal therapy------Nanotechnology（IF=3.404）

lipidnanobubbles as an ultrasound-triggered artesunate delivery system forimaging-guided,tumor-targeted chemotherapy------ OncoTargetsand Therapy(IF=2.656)

Facilesynthesis of biocompatible MoSe2 nanoparticles for efficienttargeted photothermal therapy of human lung cancer------ RSCAdvances（IF=2.963）

Biomimeticvirus-like and charge reversible nanoparticles to sequentially overcome mucusand epithelial barriers for oral insulin delivery------Acs applied materials&interfaces（IF=8.097）

A novelnear-infrared triggered dual-targeted nanoplatform for mitochondrial combinedphotothermal-chemotherapy of cancer in vitro------Nanotechnology（IF=3.404）

StableGold Nanorods Conjugated Liposomal Podophyllotoxin Nanocomposites forSynergistic Chemo-Photothermal Cancer Therapy------Journal of BiomedicalNanotechnology(5.068)

Thisproduct is for research use only and is not intended for use in humans or fordiagnostic use.